William Todd Penberthy, Ph. D.


Winter Park, Florida, United States of America

Mobile: 1(407) 951-1624 Email: WTPENBER@GMAIL.COM




Ph.D., Biochemistry, University of Tennessee, Memphis, TN

B.S., Biology, University of Central Florida, Orlando, FL



Medical Writer, 2012 - current, Winter Park, FL

Professor, 2009-2012, University of Central Florida, Orlando, FL 

Professor, 2004-2009, University of Cincinnati, Cincinnati, OH

Post-doctoral Fellow, 2000-2003, University of California, Los Angeles, CA

Post-doctoral Fellow, 1999-2000, Tufts University, Boston, MA



Orthomolecular medicine, oncology, neurodegenerative disease, cancer, cardiovascular disease, diabetes, arthritis


SUMMARY 16+ years writing/research in the biomedical scientific realm

  • Book author: The Vitamin Cure for Arthritis (2015)
  • Weekly top biomedical science newspiece from: Science Translational Medicine, other Science journals, Nature, PNAS, Neuron, other journals
  • Medical writer/researcher of physician clinical overviews for MDs: B-cell lymphoma, carcinoid, desmoid tumors, hyperleukocytosis in malignancy, Malignant brain tumors in children, aspiration pneumonia, Bartonella infections, salmonellosis, protein C deficiency, prostatitis, Raynaud’s phenomena, more
  • Needs Assessments: diabetes, systemic lupus erythematosus, pediatric multiple sclerosis, schizophrenia, insomnia disorders, generalized tonic-clonic seizures, cystic fibrosis
  • Medical technology directory reports: Comprehensive reviews focused on cutting edge medical technologies for practice/budgetary/policy decisions. Subscription only.
  • Guest executive editor: Current Pharmaceutical Design 2009; Invited reviewer for peer-reviewed journals




McConnel, Stephen and W. Todd Penberthy (2021). Reversing Chronic Kidney Disease with Niacin and Sodium Bicarbonate. Orthomolecular Medical News Service.  

Penberthy, W. Todd, and James B. Kirkland (2020 & 2012). Niacin. Present Knowledge in Human Nutrition. 10th edition, Diane Birt, J W Erdman, I MacDonald, S H Zeisel, eds. (Ames, Iowa, International Life Sciences).

Penberthy, W. Todd, Mahrou Sadri, and Janos Zempleni (2020 & 2012). Biotin. Present Knowledge in Human Nutrition. 10th edition, Diane Birt, J W Erdman, I MacDonald, S H Zeisel, eds. (Ames, Iowa, International Life Sciences).

Penberthy, W.Todd (2020 & 2013). Niacin, Riboflavin, and Thiamine, ed. Stipanuk, M.H., Caudill, M.A., eds., Biochemical, Physiological, and Molecular Aspects of Human Nutrition, 3rd ed. Elsevier/Saunders, St. Louis, Mo., pp. p.540-564.

Penberthy, W. Todd, and Robert Smith (2018). Nutritional Approaches Treatments for Multiple Sclerosis. Orthomolecular Medical News Service. 

Penberthy, W. Todd (2017). Niacin Rescues Cannibalistic Hamsters: The Historical Significance of 1940s Mandatory Niacin Enrichment. Orthomolecular Medical News Service.

Hu, L, K. Ibrahim, M. Stucki, M. Frapolli, N. Shahbeck, F. A. Chaudhry, B. Gorg, D. Haussinger, W. Todd Penberthy, T. Ben-Omran, and J. Haberle (2015). Secondary NAD+ Deficiency in the Inherited Defect of Glutamine Synthase. Journal of Inherited Metabolic Disease. 38(6):1075-83. 

Penberthy, W. Todd & Robert Smith (2015). The Vitamin Cure for Arthritis. A book for laypersons about nutritional approaches to treating arthritis. p1-237. 

Penberthy, W. Todd, and Andrew Saul. Supplements Accelerate Benzodiazepine Withdrawal: A Case Report and Biochemical Rationale

W. Todd Penberthy (2013). Ask This Question Before Taking Statins. Orthomolecular Medical News Service. 

Babak Baban, W. Todd Penberthy & Mahmood S. Mozaffari (2010). The Potential Role of Indoleamine 2,3 Dioxygenase (IDO) as a Predictive and Therapeutic Target for Diabetes Treatment: a Mythical Truth; EPMA Journal 1:46–55.

Penberthy, W. Todd (2009). Nicotinic Acid-Mediated Activation of Both Membrane and Nuclear Receptors Towards Therapeutic Glucocorticoid Mimetics for Potential Treatment of Multiple Sclerosis; PPAR Research 853707-.

Penberthy, W. Todd (guest executive editor) Current Pharmaceutical Design, published 2009. Developed theme, coordinated authors/reviewers, and provided oversight to completion. Theme: NAD Biology in Disease. 

Penberthy, W. Todd & Tsunoda, I. (2009). The Importance of NAD in Multiple Sclerosis. Current Pharmaceutical Design. 2009; 15(1): 64-99. 

Penberthy, W. Todd (2009). Nicotinamide Biology and Disease. Current Pharmaceutical Design; 15 (1) 1-2. 

Kevin S Jones, Alexander P Alimov, Horacio L Rilo, Ronald P Jandacek, Laura A Woollett, and W. Todd Penberthy (2008). A High Throughput Live Transparent Animal Bioassay to Identify Non-toxic Small Molecules or Genes that Regulate Vertebrate Fat Metabolism for Obesity Drug Development. Nutrition and Metabolism. 5:23. 

Penberthy, W. Todd. (2007). Pharmacologic Targeting of IDO-mediated Tolerance for Treating Autoimmune Disease. Current Drug Metabolism. 8: 245-266. REQUEST PDF AND I WILL SEND. 

Traver, David, Barry H. Paw, Kenneth D. Poss, W. Todd Penberthy, Shuo Lin, and Leonard I. Zon (2003). Transplantation and in vivo Imaging of Multi-lineage Engraftment in Zebrafish Bloodless Mutants. Nature Immunology. 4:1238-1246.

Penberthy, W. Todd, Ebrahim Shafizadeh, and Shuo Lin (2002). The Zebrafish as a Model for Human Disease. Frontiers in Biosciences 7, D1439-53. 



Orthomolecular Medical News Service (OMNS)

American Medical Writers Association (AMWA)

American Association for the Advancement of Science (AAAS)

Global Alliance of Publication Professionals (GAPP)



Presentations & Meetings

  • Invited presentation to the Mayo Clinic, May 2009, NAD-Centric Pharmacologic Approaches & Obesity/COPD Animal Modeling Using Zebrafish.
  • Invited presentation and Travel Award to The 4th Annual Metabolic Diseases World Summit, Boston, MA 2008: A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development
  • Invited speaker at Case Western TREC Retreat 2008, NAD Pharmacotherapeutics: Zebrafish-based Small Molecule Studies of Lipid Metabolism with Implications for Cancer and Multiple Sclerosis.” 
  • Invited presentation and Travel Award to PARP 2008, Tucson, Arizona 
  • Invited speaker at the Department of Human Nutrition at Ohio State University: The Zebrafish Genetic Model Organism for Studying Nutrient Function, Oct. 2007, Columbus, Ohio



Diabetes, PPAR Research, Mutation Research, Developmental Dynamics, Immunology Letters, Journal of Nutrition, Antiviral Research, Brain Research Bulletin, Schizophrenia Research, Molecular Biology Reports, Development, Nucleic Acid Research