W. Todd Penberthy, PhD (biochemistry)


I am a continuing medical education writer and researcher developing courses describing the latest approaches for physicians, attending medical conferences, and reporting on translational medicine discoveries. 


My expertise includes focus on all things Vitamin B3 => NAD, particularly  the vitamin B3 isomer niacin (&  related vitamin B3s), which is uniquely the best in my opinion given the 2nd, non-vitamin flush pathway that has its own distinctive benefits as the gold standard for correcting lipodystrophy (elevated triglycerides, low HDL, high VLDL, high Lp(a), and cholesterol), but there is so much more. 



Restoring Gene Function Medicine


One of the pinnacles of biomedical science has been the identification of the essential molecules (vitamins and certain minerals, fatty acids, and amino acids) and the >20,000 genes with the biochemistry, which at the end of the day defines the chemical activities, of how this is done 


Today we have all of the genes, sequences, and binding domains that require said vitamins/minerals/nutrients for life to exist and persist as determined from basic cell culture experiments that determined which nutrients are required for cellular life. 


As one gets older, you cannot absorb these things as well, and you may need more if you are battling infections, toxins, and/or uncontrolled growths, but fortunately one can restore gene function you can knock all these things down or eliminate these things, but you must know. 


Safety first and these essential molecules literally preserve life itself daily.


Therapeutic areas:

  • Cardiovascular disease / lipids / cholesterol / event risk 
  • Chronic kidney disease
  • Diabetes 
  • Cancer
  • Neurological disease 



W. "Todd" Penberthy, PhD

PhD in Biochemistry, U. Tennessee, Memphis, 1997

Tufts, Medical College of Georgia, UCLA (1997-2004)


Mentored by Abram Hoffer, MD, PhD (2004-2007; b1917-d2007)


Continuing Medical Education writer research and teaching physicians the latest treatments so they can maintain board certifications and keep up to date including:


Cancers: triple negative breast cancer, HER2+ breast cancer, HR+ breast cancer, small cell lung carcinoma and NSCLC, Desmoid tumors 

Neurodegenerative diseases: Progressive multiple sclerosis, Huntington’s disease

Psychiatric: Depression, anxiety, schizophrenia

Cardiovascular: Heart failure, Lidodystrophy 

Renal: IgA nephropathy


Diabetes & chronic kidney disease





International niacin/NAD expertise, Pubmed publications


University textbook author (niacin, vitamins B1-B3, biotin); PKN 2020  BPMAHN 2018 & 2012 both


Member of the International Society of Orthomolecular Medicine


Author: The Vitamin Cure for Arthritis; forwards to Niacin, The Real Story

Regularly attends medical conferences


Invited presentation to The 50th International Society for Orthomolecular Medicine conference, “NAD History - Niacin Before & Forever After”


Presentations March, 2021 to Society for the Advancement of Hormones and Healthy Aging Medicine Malaysia: (first talk) “Niacin/NAD Your Gateway to Good Health & (2nd talk) Addressing the Challenges of Dementia with Orthomolecular Medicine


Editorial board member of the Orthomolecular Medical News Service & Journal of Orthomolecular Medicine, member of the International Society of Orthomolecular Medicine



Professor; U. of Cincinnati & U. of Central Florida; Independently directing research (2004-2012) 


Mayo Clinic 2009, Case Western Reserve 2009